Sam Toole

Partner, Healthcare

Thesis

We’re all patients in a broken healthcare system. AI creates a once-in-a-lifetime opportunity to redefine how care is delivered. The implications are massive — better health for millions, lower costs for families, and a happier society.

About

Sam partners with founders obsessed with transforming the broken healthcare system from the ground up. The former entrepreneur and operator has a non-traditional path into investing, having started an e-commerce brand and a surf school before shifting into the world of healthcare at Nomad Health. He's most energized by close collaboration with founders—ideating on strategy, diving into challenging problems, and discovering solutions through creative thinking together.

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Get in touch

LinkedIn
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Investments

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Building healthier communities

Founders

Jon Collins

View company
Invested
2024
Stage
Series A

Building healthier communities

Connecting healthcare payors and EMS agencies, creating an environment where 911 callers receive appropriate and cost-effective care.

Founded
2024
HQ
New York, NY
Investor
Sam Toole
Invested
2024
Founders

Jon Collins

Stage
Series A
Visit Website
Healthcare

Transforming clinical trials and precision medicine

Founders

Elliott Green

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Invested
2021
Stage
Seed

Transforming clinical trials and precision medicine

Leveraging AI and data to drive pharmaceutical and precision medicine innovation.

Founded
2020
HQ
New York, NY
Investor
Sam Toole
Invested
2021
Founders

Elliott Green

Stage
Seed
Visit Website
Healthcare

Navigating seniors through healthcare

Founders
Invested
2025
Stage
Pre-Seed

Navigating seniors through healthcare

Empowering people to access the best care possible through personalized navigation and advocacy

Founded
HQ
Investor
Sam Toole
Invested
2025
Founders

Stealth

Stage
Pre-Seed
Visit Website
Healthcare

The infrastructure layer for health plans

Founders

Cédric Kovacs-Johnson

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Invested
2019
Stage
Series A

The infrastructure layer for health plans

Making health plan innovation fast, flexible, and less expensive.

Founded
2017
HQ
New York, NY
Investor
Sam Toole
Invested
2019
Founders

Cédric Kovacs-Johnson

Stage
Series A
Visit Website
Healthcare

The essential ecosystem for senior living

Founders

Alex Hejnosz
Michael Wang

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Invested
2024
Stage
Series B

The essential ecosystem for senior living

The most complete ecosystem in senior living, bringing together care planning, staff efficiency, fall prevention, and eCall into one seamless platform.

Founded
2016
HQ
New York, NY
Investor
Sam Toole
Invested
2024
Founders

Alex Hejnosz
Michael Wang

Stage
Series B
View Company Page
Visit Website
Healthcare

Intelligent health plan network

Founders

Josh Poretz

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Invested
2021
Stage
Seed

Intelligent health plan network

Providing real-time insights and analysis for health plan provider networks

Founded
2021
HQ
New York, NY
Investor
Sam Toole
Invested
2021
Founders

Josh Poretz

Stage
Seed
Visit Website
Healthcare

Age safely at home

Founders

Seung Bak
Oren Shatken
Romanos Fessas

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Invested
2021
Stage
Series A

Age safely at home

Preserving independence at scale — from home modifications to critical insights that advance value-based care.

Founded
2020
HQ
New York, NY
Investor
Sam Toole
Invested
2021
Founders

Seung Bak
Oren Shatken
Romanos Fessas

Stage
Series A
Visit Website
Healthcare

The Medicare Advantage operating system

Founders

James Jiang
Alex Zhang

View company
Invested
2020
Stage
Series B

The Medicare Advantage operating system

Partnering with brokers and health plans to esnure that seniors enroll in the right Medicare plan, maximize benefits, and take control of their health.

Founded
2020
HQ
New York, NY
Investor
Sam Toole
Invested
2020
Founders

James Jiang
Alex Zhang

Stage
Series B
View Company Page
Visit Website
Healthcare

Achieve success in value‑based care

Founders

Michael Meng

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Invested
2018
Stage
Series C

Achieve success in value‑based care

Delivering the healthcare payment model to ensure providers and their staff are reimbursed and rewarded for improving patient outcomes.

Founded
2018
HQ
New York, NY
Investor
Sam Toole
Invested
2018
Founders

Michael Meng

Stage
Series C
Visit Website
Healthcare

Helping independent provider groups thrive

Founders

Peter Shalek
Nitin Joshi

View company
Invested
2024
Stage
Series A

Helping independent provider groups thrive

Transforming how independent practices operate by leveraging AI to automate repetitive, time-consuming work that bogs down healthcare providers.

Founded
2024
HQ
San Francisco, CA
Investor
Sam Toole
Invested
2024
Founders

Peter Shalek
Nitin Joshi

Stage
Series A
View Company Page
Visit Website
Healthcare

Founder Testimonial

Working with Sam and the Primary team over the past two years has been a true partnership. They’ve rolled up their sleeves, supported us at every turn, and played a hands-on role in building Inspiren. I couldn’t imagine doing this without them.

Alex Hejnosz
CEO & Co-Founder

Associate

Hannah McQuaid

Senior Associate, Healthcare
LinkedIn

Hannah is focused on healthcare investments. She was previously at Ansa Capital, partnering with early growth-stage companies across healthcare and enterprise software. Before that, she held roles at Pruven Capital and Guardian Life’s venture group, working with companies like Particle Health, Angle Health, and Unite Us. A New York native from Queens, Hannah spends her free time running, cooking, and exploring new streetwear brands.

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Writing

Why we doubled down on Inspiren

By {author name}

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